Androgens and hair loss

Question from Lucien B.

What is DHT and what does it have to do with hair loss and androgen hormones?

Clauderer's answer

DHT (dihydrotestosterone) is a hormone of the androgen family. This hormone is secreted when the enzyme 5-alpha reductase meets the androgens that normally circulate in the blood. This new androgen, DHT, is much more powerful than normal androgens and is the cause of so-called androgenetic hair loss in both men and women.

In a healthy hair follicle, the 5-alpha reductase enzyme remains inactive. But in a genetically predisposed follicle, androgens, transformed into DHT by 5-alpha, act on the hair follicles. hair life cycles. With each new cycle, they increasingly shorten the anagen phase of growth and, on the contrary, prolong the telogen resting phase, abnormally delaying the start of new growth. Eventually, the hair follicle becomes miniaturised, producing thinner and thinner hair that becomes down (see diagram below). Eventually, the follicle produces nothing at all: this is baldness.

Action of androgens on hair
action of androgens on hair



These harmful effects caused by the androgen DHT can be reversed by the anti-androgen plant active ingredients in Clauderer Serums 6R and 7R. In vivo tests have shown that the rate of hair growth is not affected by androgens when Clauderer Serums 6R and 7R were regularly applied to androgenetic scalps.

Jean-François Cabos

Jean-François Cabos is the creator of a unique hair care method based on the research he coordinated, which led to the publication of the book "Cheveux, Racines de Vie" with Hélène Clauderer by Robert Laffont (Collection "Réponses/ Santé").

Leave a Reply

Your email address will not be published. Required fields are marked *